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Senior Global Medical Director, Dementia

GlaxoSmithKline
United States, Pennsylvania, Collegeville
1250 South Collegeville Road (Show on map)
Sep 19, 2025
Site Name: UK - London - New Oxford Street, 200 CambridgePark Drive, Belgium-Wavre, USA - Pennsylvania - Upper Providence
Posted Date: Sep 19 2025

Job Purpose

The Senior Global Medical Affairs Director role is a unique opportunity for an experienced, innovative, and proactive medical affairs professional to provide strategic leadership within GSK's Global Therapeutic Areas (TAs). You will play a pivotal role in setting and delivering the long-term disease and medicine strategy for a key portfolio or asset, focused on Shingles and Dementia, with global impact.

This exciting role requires multi-functional matrix management, influencing major markets, as well as collaboration across commercial, clinical, and medical affairs functions. By leveraging partnerships with external experts, patient advocacy groups, and internal stakeholders, you will ensure seamless global-to-local execution of congresses, scientific communications, medical training, and personalized digital engagement tactics.

The successful applicant will report to the Vice President, Global Medical Lead (GML) for Shingles, providing strategic accountability for all activities aligned to the asset strategy, while leading and implementing key projects as necessary.

Key Responsibilities

Core Responsibilities:

  • Provide strong scientific leadership and agility while developing deep subject matter expertise on Shingles and Dementia therapy areas and driving proactive strategic planning.
  • Collaborate extensively with Local Operating Company (LOC) teams to understand landscape, market value drivers, unmet medical needs, and timelines for deliverables required for their success.
  • Work with the GML to define key areas of unmet need and gather deep external expert insights on disease strategy, product positioning, data gaps, market access, and evidence generation strategy.
  • Bridge data generation, market access, and healthcare shaping strategies for Shingles and Dementia across therapeutic areas.
  • Define and execute the Global Strategic Plan and lead the Global Medical Operational Plan for Shingles and Dementia, working with key market leads and cross-functional partners to define medical strategy, resourcing, and key performance indicators.
  • Partner across the internal ecosystem and external networks to deliver Medical Plans that prioritize external impact, on time and on budget.
  • Drive patient advocacy group engagement to advance understanding of unmet needs and deliver impactful global disease awareness activities.
  • Ensure colleagues are equipped with robust knowledge of emerging clinical evidence, supporting their training needs through high-quality scientific materials.
  • Partner with teams across Global Product Strategy, Market Access, and LOCs to advise on claims and material review.
  • Oversee medical governance by managing product-related issues with potential impact on patient safety and ensuring risk mitigation strategies are in place.
  • Foster a culture of innovation, agility, and faster solutions for patients.

Evidence Generation:

  • Collaborate across the ecosystem, including R&D, RWE & HO Research, Global Product Strategy, and LOC teams, to identify and prioritize evidence generation needs.
  • Work with key Market Leads and Clinical Development Leads to design Phase 3b/4 and Value Evidence and Outcomes studies that inform future treatment paradigms and decision-making for healthcare providers and payers.
  • Review investigator-sponsored study (ISS) proposals to assess their strategic alignment and scientific merit, in partnership with R&D, safety, biostatistics, and other experts.

Scientific Communications and Engagement:

  • Define and execute global scientific communication plans in partnership with the Scientific Communications and Publications Team.
  • Develop and communicate strategic publications plans to ensure alignment with the medical strategy.
  • Lead quarterly development and communication of Shingles and Dementia news flow.
  • Build a collaborative network of external experts (HCPs, patients, payors, and regulators) to advance clinical care and patient outcomes, in partnership with LOC Medical teams.
  • Oversee scientific review and/or approval of promotional and non-promotional materials across all channels, including digital and congress materials.

Leadership Responsibilities:

  • Take the initiative to identify opportunities for innovation and improvement within the global medical affairs strategy and execution across all indications.
  • Inspire and motivate team members across the matrix organization, fostering collaboration and engagement.
  • Lead cross-functional initiatives that drive strategic priorities, ensuring alignment and execution across global and local teams.
  • Provide thought leadership and strategic direction to anticipate future challenges and opportunities.
  • Act as a mentor to junior medical affairs professionals, fostering a culture of excellence and professional growth.

Qualifications

Essential:

  • MD/MBBS/PharmD or PhD.
  • Experience in late-phase (Phase 2 or 3) clinical development within neurology.
  • Experience in Medical Affairs, including roles in LOCs and Global teams.
  • Experience in pre/peri-launch and lifecycle management phases of assets.
  • Experience in Evidence Generation, Scientific Communication, and Omnichannel strategies.
  • Experience of regulatory and clinical development strategies across early and late stages.
  • Experience in presenting or speaking at conferences and congresses.
  • Experience in managing multiple projects, budgets, and interactions simultaneously.
  • Experience working within matrix environments.

Preferred:

  • Board-certified Neurologist or PhD in Neurology
  • Experience in business development of pharmaceutical assets.
  • Robust understanding of internal and external codes of practice and regulations.
  • Proven matrix leadership, with the ability to build strong networks and manage complexity and cultural diversity.
  • Experience in medical support for regulatory interactions and payor dossiers in dementia settings.
  • General understanding of statistics, safety, and regulatory requirements.
  • Outstanding listening, communication, and collaborative leadership skills, with the ability to interface with a wide range of internal and external stakeholders.
  • Evidence of alignment with GSK Values.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

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