New

Research Lab Tech I NEUROLOGY RESEARCH Renthal Lab

Brigham and Women's Hospital
United States, Massachusetts, Boston
60 Fenwood Road (Show on map)
Jan 24, 2025
Summary: Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Does this position require Patient Care? No Essential Functions - Perform laboratory experiments following established protocols and procedures. - Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines. - Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed. - Record experimental data accurately and maintain organized records of procedures, protocols, and results. - Compile and analyze data using appropriate statistical and analytical methods. - Assist in data interpretation and presentation, contributing to research findings and reports. Education Bachelor's Degree required. Experience At least 1 year of research experience required. Principal Duties and Responsibilities: Research, develop, design, execute and interpret research experiments. The successful applicant will initially carry out established protocols they will learn on the job. Over time, it is expected that the successful applicant will be able to design and execute their own experiments. Contribute to scientific literature, reports, journals and presentations. Investigate, create, and develop new methodologies for research advancement. Contribute to a positive, respectful, and scholarly lab environment. Read, teach, enjoy. Maintain an organized record of laboratory experiments. Other project-related duties as assigned. Competencies Required: Ability to work independently and with a multidisciplinary team. Background in molecular biology including cloning and PCR. Prior experience working with mice in a research setting. Familiarity with Excel, and either R, Python, or Matlab. Good oral and written communication skills. The successful applicant should be comfortable presenting their work through oral presentations and written reports. Analytical skills, the ability to troubleshoot technical or research roadblocks, and to interpret data with biological relevance in mind. Detail-oriented with excellent organizational skills and ability to prioritize a variety of tasks. Knowledge, Skills and Abilities: Strong theoretical and practical knowledge of laboratory techniques and procedures. Familiarity with common laboratory equipment and instruments used in research experiments. Proficiency in data collection, analysis, and scientific software tools. Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively. Strong problem-solving skills and the ability to troubleshoot technical issues. Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges. Working Conditions: The successful applicant will have their own desk and laboratory bench space located in the Hale Building for Transformative Medicine at Brigham and Women's Hospital. There is a mouse facility in the same building as well as several additional research cores. Copious amounts of coffee and tea are available to all trainees. We are seeking a highly-motivated and creative research assistant to work on cutting-edge projects aimed at developing next-generation treatments for chronic pain and migraine. Under the supervision of Principal Investigator, Dr. William Renthal at Brigham and Women's Hospital and Harvard Medical School, the successful applicant will carry out and design well-controlled experiments and publish their results. The successful applicant will receive scientific training, professional development, and mentorship within the Renthal Lab at Brigham and Women's Hospital. The research interests of the Renthal Lab focus on the genetics and epigenomics of chronic pain and headache. Projects will leverage recent advances in single-cell genomics to characterize molecular features that are unique to nociceptors, which are the peripheral sensory neurons that transmit pain signals to the brain. The successful applicant will aid in the design of targeted pain and headache therapeutics, including novel gene therapy vectors. This research will require skill development in molecular biology including cloning, CRISPR/Cas9 genome editing, Next-Generation Sequencing, bioinformatics, and neuronal physiology. Additionally, there will be ample opportunities to collaborate with other labs within Harvard Medical School and the surrounding hospitals and research institutions. Prior research experience is preferred. As a 2-year commitment is required, this is a great opportunity for a candidate interested in subsequently applying to graduate or medical school. Prior research assistants of Dr. Renthal have advanced to graduate training at Harvard, UCSF, Washington University, and McGill University. This is a 12-month term position renewable contingent on funding and work performance. Offer contingent upon successful completion of a pre-placement medical evaluation. To apply for this position, applicants should submit: CV Potential start date Contact information of three references The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.